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SECURITIES AND EXCHANGE COMMISSION

Washington D.C. 20549

SCHEDULE 13G

Amendment No. 3

Under the Securities Exchange Act of 1934

SPECTRX, INC.

(Name of Issuer)

Common Stock, $0.001 Par Value

(Title of class of Securities)

847635109

(CUSIP Number)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed.

[ ] Rule 13d-1(b)

[ ] Rule 13d-1(c)

[X] Rule 13d-1(d)

The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior coverage page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of this section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

E. C. Johnson as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Bruce I. Crocker as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

12/30/76 for the Children of Juliet Lea Hillman Simonds I.D. #25-6193084

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

12/30/76 for the Children of Audrey Hillman Fisher I.D. #25-6193085

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

12/30/76 for the Children of Henry Lea Hillman, Jr. I.D.. #25-6193086

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

12/30/76 for the Children of William Talbott Hillman I.D. #25-6193087

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Henry L. Hillman as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Elsie Hilliard Hillman as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Charles G. Hadley

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Hal S. Broderson

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Ronald J. Brenner

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Henry L. Hillman, Elsie Hilliard Hillman and C. G Grefenstette

Trustees of the Henry L. Hillman Trust U/A Dated November 18, 1985

I.D. # 18-2145466

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

The Hillman Company I.D. # 25-1011286

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Wilmington Investments, Inc. I.D. # 51-0034468

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Wilmington Equities, Inc. I.D. # 51-0411204

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Wilmington Securities, Inc. I.D. # 51-0114700

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each 0

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Wilmington Interstate Corporation I.D. # 51-0313966

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Hillman/Dover Limited Partnership I.D. # 51-0286294

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Cashon Biomedical Associates L.P. I.D. # 23-2555178

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 0 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

0 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Hillman Medical Ventures 1995 L.P. I.D.# 51-0364601

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Hillman Medical Ventures 1996 L.P. I.D.# 51-0372016

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

CUSIP NO. 847635109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Hillman Medical Ventures 1997 L.P. I.D.# 52-2028335

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Delaware

Number of 5. Sole Voting Power

Shares 0

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 0

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

12. Type of Reporting Person

Item 1(a) Name of Issuer

Spectrx, Inc.

Item 1(b) Address of Issuer's Principal Executive Office:

4955 Avalon Ridge Parkway, Suite 300

Norcross, GA 30071

Item 2(a) Name of Person Filing:

(i) Hillman Medical Ventures 1995 L.P., a Delaware Limited

Partnership whose general partners are Hillman/Dover Limited

Partnership and Cashon Biomedical Associates, L.P.

(ii) Hillman Medical Ventures 1996 L.P., a Delaware Limited

Partnership whose general partners are Hillman/Dover Limited

Partnership and Cashon Biomedical Associates, L.P.

(iii) Hillman Medical Ventures 1997 L.P., a Delaware Limited

Partnership whose general partners are Hillman/Dover Limited

Partnership and Cashon Biomedical Associates, L.P.

(iv) Hillman/Dover Limited Partnership, a Delaware Limited

Partnership whose general partner is Wilmington Securities, Inc.

(v) Cashon Biomedical Associates, L.P., a Delaware Limited

Partnership whose general partners are Charles G. Hadley,

Hal S. Broderson and Ronald J. Brenner

(vi) Wilmington Interstate Corporation, a wholly-owned subsidiary of

Wilmington Equities, Inc.

(vii) Wilmington Securities, Inc., a wholly-owned subsidiary of

Wilmington Equities, Inc.

(viii) Wilmington Equities, Inc., a wholly-owned subsidiary of

Wilmington Investments, Inc.

(ix) Wilmington Investments, Inc, a wholly-owned subsidiary of

The Hillman Company.

(x) The Hillman Company, a corporation controlled by the HLH

Trust.

(xi) Henry L. Hillman, Elsie Hilliard Hillman and C. G. Grefenstette

Trustees of the Henry L. Hillman Trust U/A dated November 18,

1985 (the "HLH Trust").

(xii) C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees

U/A/T dated 12/30/76 for the Children of Juliet Lea Hillman

Simonds (the "1976 JLHS Trust).

(xiii) C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees

U/A/T dated 12/30/76 for the Children of Audrey Hillman Fisher

(the "1976 AHF Trust).

(xiv) C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees

U/A/T dated 12/30/76 for the Children of Henry Lea Hillman, Jr.

(the "1976 HLH, Jr. Trust).

(xv) C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees

U/A/T dated 12/30/76 for the Children of William Talbott Hillman

(the "1976 WTH Trust).

(xvi) Ronald J. Brenner

(xvii) Hal S. Broderson

(xviii) Charles G. Hadley

(xix) Elsie Hilliard Hillman

(xx) Henry L. Hillman

(xxi) Bruce I. Crocker

(xxii) E. C. Johnson

(xxiii) C. G. Grefenstette

Item 2(b) Address of the principal Business Office:

Hillman Medical Ventures 1995 L.P., Hillman Medical

Ventures 1996 L.P., Hillman Medical Ventures 1997 L.P.,

Hillman/Dover Limited Partnership, Wilmington Interstate Corporation,

Wilmington Securities, Inc., Wilmington Equities, Inc. and Wilmington

Investments, Inc.

824 Market Street, Suite 900

Wilmington, DE 19801

The Hillman Company

330 Grant Street, Suite 1900

Pittsburgh, PA 15219

The 1976 JLHS Trust, the 1976 AHF Trust, the 1976 HLHJR Trust

The 1976 WTH Trust and the HLH Trust

330 Grant Street, Suite 1800

Pittsburgh, PA 15219

Cashon Biomedical Associates L.P., Charles G. Hadley, Hal S.

Broderson and Ronald J. Brenner

One Tower Bridge, Suite 1350

100 Front Street

West Conshohocken, Pennsylvania 19428

Elsie Hilliard Hillman, Henry L. Hillman, E. C. Johnson,

C. G. Grefenstette and Bruce I. Crocker

330 Grant Street, Suite 2000

Pittsburgh, Pennsylvania 15219

Item 2(c) Citizenship:

Hillman Medical Ventures 1995 L.P., Hillman Medical Ventures

1996 L.P., Hillman Medical Ventures 1997, Hillman/Dover

Limited Partnership and Cashon Biomedical Associates L.P. are

Delaware limited partnerships.

Wilmington Interstate Corporation, Wilmington Securities, Inc,

Wilmington Equities, Inc. and Wilmington Investments, Inc.

are Delaware corporations.

The Hillman Company is a Pennsylvania corporation.

The 1976 JLHS Trust, the 1976 AHF Trust, the 1976 HLHJR Trust

the 1976 WTH Trust and the HLH Trust are Pennsylvania trusts.

Elsie Hilliard Hillman, Henry L. Hillman, E. C. Johnson,

C. G. Grefenstette, Bruce I. Crocker, Charles G. Hadley, Hal S.

Broderson and Ronald J. Brenner are U.S. citizens.

Item 2(d) Title of Class of Securities:

Common Stock, $.001 Par Value

Item 2(e) CUSIP Number

847635109

Item 3 Not Applicable

Item 4 Ownership:

101,860 shares of Common Stock were sold in a private sale by

Hillman Medical Ventures 1995 L.P., a Delaware limited partnership

("HMV 95"). Hillman/Dover Limited Partnership and Cashon

Biomedical Associates L.P. are general partners of HMV 95. Wilmington

Securities, Inc. is the sole general partner of Hillman/Dover Limited

Partnership. Wilmington Securities, Inc. is a wholly-owned subsidiary

of Wilmington Equities, Inc. Wilmington Equities, Inc. is a wholly-owned

subsidiary of Wilmington Investments, Inc. Wilmington Investments, Inc.

is a wholly-owned subsidiary of The Hillman Company, which is

controlled by the HLH Trust. Charles G. Hadley, Hal S. Broderson and

Ronald J. Brenner are general partners of Cashon Biomedical Associates

L.P.

423,102 shares of Common Stock were sold in a private sale by

Hillman Medical Ventures 1996 L.P., a Delaware limited partnership

("HMV 96"). Hillman/Dover Limited Partnership and Cashon

Biomedical Associates L.P. are general partners of HMV 96. Wilmington

Securities, Inc. is the sole general partner of Hillman/Dover Limited

Partnership. Wilmington Securities, Inc. is a wholly-owned subsidiary

of Wilmington Equities, Inc. Wilmington Equities, Inc. is a wholly-owned

subsidiary of Wilmington Investments, Inc. Wilmington Investments, Inc.

is a wholly-owned subsidiary of The Hillman Company, which is

controlled by the HLH Trust. Charles G. Hadley, Hal S. Broderson and

Ronald J. Brenner are general partners of Cashon Biomedical Associates

L.P.

75,000 shares of Common Stock were sold in a private sale by

Hillman Medical Ventures 1997 L.P., a Delaware limited partnership

("HMV 97"). Hillman/Dover Limited Partnership and Cashon

Biomedical Associates L.P. are general partners of HMV 97. Wilmington

Securities, Inc. is the sole general partner of Hillman/Dover Limited

Partnership. Wilmington Securities, Inc. is a wholly-owned subsidiary

of Wilmington Equities, Inc. Wilmington Equities, Inc. is a wholly-owned

subsidiary of Wilmington Investments, Inc. Wilmington Investments, Inc.

is a wholly-owned subsidiary of The Hillman Company, which is

controlled by the HLH Trust. Charles G. Hadley, Hal S. Broderson and

Ronald J. Brenner are general partners of Cashon Biomedical Associates

L.P.

82,637 shares of Common Stock were sold in a private sale by

Wilmington Interstate Corporation, a wholly-owned subsidiary of

Wilmington Equities, Inc. Wilmington Equities, Inc. is a wholly-owned

subsidiary of Wilmington Investments, Inc. Wilmington Investments, Inc.

is a wholly-owned subsidiary of The Hillman Company, which is

controlled by the HLH Trust.

9,905 shares of Common Stock were sold in a private sale by

Wilmington Securities, Inc., a wholly-owned subsidiary of Wilmington

Equities, Inc. Wilmington Equities, Inc. is a wholly-owned subsidiary

of Wilmington Investments, Inc. Wilmington Investments, Inc.

is a wholly-owned subsidiary of The Hillman Company, which is

controlled by the HLH Trust.

494,101 shares of Common Stock were sold in a private sale by

Henry L. Hillman, Elsie Hilliard Hillman and C. G. Grefenstette,

Trustees of the Henry L. Hillman Trust U/A dated November 18, 1985

a Pennsylvania revocable trust. C. G. Grefenstette shares power to

vote or to direct the vote and shares power to dispose or to direct the

disposition of the shares of stock owned by the 1976 Trusts, the

HLH Trust, Wilmington Interstate Corporation and Wilmington

Securities, Inc. Henry L. Hillman shares power to vote or to direct the

vote and shares power to dispose or direct the disposition of the shares

of stock owned by the HLH Trust, Wilmington Interstate Corporation and

Wilmington Securities, Inc.. Elsie Hilliard Hillman shares power

to vote or to direct the vote and shares power to dispose or to direct the

disposition of the shares of stock owned by the HLH Trust, Wilmington

Interstate Corporation and Wilmington Securities, Inc.

98,033 shares of Common Stock were sold in a private sale by

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

December 30, 1976 for the Children of Juliet Lea Hillman Simonds

(together with the three trusts of even date named below, the "1976

Trusts"), a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts

the HLH Trust, Wilmington Interstate Corporation and Wilmington

Securities, Inc.

98,033 shares of Common Stock were sold in a private sale by

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

December 30, 1976 for the Children of Audrey Hillman Fisher,

a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts

the HLH Trust, Wilmington Interstate Corporation and Wilmington

Securities, Inc.

98,033 shares of Common Stock were sold in a private sale by

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

December 30, 1976 for the Children of Henry Lea Hillman, Jr.,

a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts,

the HLH Trust, Wilmington Interstate Corporation and Wilmington

Securities, Inc.

98,033 shares of Common Stock were sold in a private sale by

C. G. Grefenstette, E. C. Johnson and Bruce I. Crocker, Trustees U/A/T dated

December 30, 1976 for the Children of William Talbott Hillman,

a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts,

the HLH Trust, Wilmington Interstate Corporation and Wilmington

Securities, Inc.

(b) Percent of Class

(i) sole power to vote or direct the vote

(ii) shared power to vote or to direct the vote

0 (See Item (4)(a))

(iii) sole power to dispose or to direct the disposition of

(iv) shared power to dispose or to direct the disposition of

0 (See Item (4)(a))

Item 5 Ownership of Five Percent or Less of a Class:

Not Applicable

Item 6 Ownership of More than Five Percent on Behalf of Another Person:

Not Applicable

Item 7 Identification and Classification of the Subsidiary Which Acquired

The Security being Reported on by the Parent Holding Company

Not Applicable

Item 8 Identification and Classification of Members of the Group:

Not Applicable

Item 9 Notice of Dissolution of Group:

Not Applicable

Item 10 Certification:

By signing below we certify that, to the best of our knowledge and

belief, the securities referred to above were not acquired and are not

held for the purpose of or with the effect of changing or influencing the

control of the issuer of the securities and were not acquired and are not

held in connection with or as a participant in any transaction having

that purpose or effect.

(Intentionally Left Blank)

SIGNATURES

After reasonable inquiry and to the best of my knowledge and belief, I certify

That the information set forth in this statement is true, complete and correct.

HILLMAN MEDICAL VENTURES 1995 L.P.

By Hillman/Dover Limited Partnership

a General Partner

By Wilmington Securities, Inc., the sole

General Partner

By: ___/s/ Andrew H. McQuarrie_________

Andrew H. McQuarrie President

By Cashon Biomedical Associates L.P.,

a General Partner

By: _______/s/ Charles G. Hadley ________

Charles G. Hadley, General Partner

By: ______/s/ Hal S. Broderson _________

Hal S. Broderson, General Partner

By: _____/s/ Ronald J. Brenner _________

Ronald J. Brenner, General Partner

HILLMAN MEDICAL VENTURES 1996 L.P.

By Hillman/Dover Limited Partnership

a General Partner

By Wilmington Securities, Inc., the sole

General Partner

By: ___/s/ Andrew H. McQuarrie_________

Andrew H. McQuarrie President

By Cashon Biomedical Associates L.P.,

a General Partner

By: _______/s/ Charles G. Hadley ________

Charles G. Hadley, General Partner

By: ______/s/ Hal S. Broderson _________

Hal S. Broderson, General Partner

By: _____/s/ Ronald J. Brenner _________

Ronald J. Brenner, General Partner

HILLMAN MEDICAL VENTURES 1997 L.P.

By Hillman/Dover Limited Partnership

a General Partner

By Wilmington Securities, Inc., the sole

General Partner

By: ___/s/ Andrew H. McQuarrie_________

Andrew H. McQuarrie President

By Cashon Biomedical Associates L.P.,

a General Partner

By: _______/s/ Charles G. Hadley ________

Charles G. Hadley, General Partner

By: ______/s/ Hal S. Broderson _________

Hal S. Broderson, General Partner

By: _____/s/ Ronald J. Brenner _________

Ronald J. Brenner, General Partner

HILLMAN/DOVER LIMITED PARTNERSHIP

By Wilmington Securities, Inc., the sole

General Partner

By: ___/s/ Andrew H. McQuarrie_________

Andrew H. McQuarrie President

CASHON BIOMEDICAL ASSOCIATES L.P.

By: _______/s/ Charles G. Hadley ________

Charles G. Hadley, General Partner

By: ______/s/ Hal S. Broderson _________

Hal S. Broderson, General Partner

By: _____/s/ Ronald J. Brenner _________

Ronald J. Brenner, General Partner

WILMINGTON INTERSTATE CORPORATION

By: /s/ Andrew H. McQuarrie

Andrew H. McQuarrie

President

WILMINGTON SECURITIES, INC.

By: /s/ Andrew H. McQuarrie

Andrew H. McQuarrie

President

WILMINGTON EQUITIES, INC.

By: /s/ Andrew H. McQuarrie

Andrew H. McQuarrie

President

WILMINGTON INVESTMENTS, INC.

By: /s/ Andrew H. McQuarrie

Andrew H. McQuarrie

Vice President

THE HILLMAN COMPANY

By: /s/ Joseph C. Manzinger

Joseph C. Manzinger

President

HENRY L. HILLMAN, ELSIE HILLIARD HILLMAN

AND C. G. GREFENSTETTE, TRUSTEES OF THE

HENRY L. HILLMAN TRUST U/A DATED

NOVEMBER 18, 1985

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

C. G. GREFENSTETTE , E. C. JOHNSON AND

BRUCE I CROCKER, TRUSTEES U/A/T DATED

DECEMBER 30, 1976 FOR THE CHILDREN

OF JULIET LEA HILLMAN SIMONDS

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ E. C. Johnson

E. C. Johnson, Trustee

/s/ Bruce I. Crocker

Bruce I. Crocker, Trustee

C. G. GREFENSTETTE , E. C. JOHNSON AND

BRUCE I CROCKER, TRUSTEES U/A/T DATED

DECEMBER 30, 1976 FOR THE CHILDREN

OF AUDREY HILLMAN FISHER

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ E. C. Johnson

E. C. Johnson, Trustee

/s/ Bruce I. Crocker

Bruce I. Crocker, Trustee

C. G. GREFENSTETTE , E. C. JOHNSON AND

BRUCE I CROCKER, TRUSTEES U/A/T DATED

DECEMBER 30, 1976 FOR THE CHILDREN

OF HENRY LEA HILLMAN, JR.

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ E. C. Johnson

E. C. Johnson, Trustee

/s/ Bruce I. Crocker

Bruce I. Crocker, Trustee

C. G. GREFENSTETTE , E. C. JOHNSON AND

BRUCE I CROCKER, TRUSTEES U/A/T DATED

DECEMBER 30, 1976 FOR THE CHILDREN

OF WILLIAM TALBOTT HILLMAN

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ E. C. Johnson

E. C. Johnson, Trustee

/s/ Bruce I. Crocker

Bruce I. Crocker, Trustee

/s/ C. G. Grefenstette

C. G. Grefenstette

/s/ E. C. Johnson

E. C. Johnson

/s/ Bruce I. Crocker

Bruce I. Crocker

/s/ Henry l. Hillman

Henry L. Hillman

/s/ Elsie Hilliard Hillman

Elsie Hilliard Hillman

/s/ Charles G. Handley

Charles G. Hadley

/s/ Hal S. Broderson

Hal S. Broderson

/s/ Ronald J. Brenner

Ronald J. Brenner

February 10, 2006

Dated